PRF BioFiller

The 100% natural alternative to traditional fillers for a refreshed, rejuvenated appearance.


PRF BioFiller is a 100% natural alternative to traditional fillers that uses growth factors and proteins from your own blood to restore lost volume and stimulate collagen within the skin. Produced purely by processing your own blood in a specific manner without any additives, PRF BioFiller can be used much like a conventional Filler would be used, including to add volume to the cheeks, lips, temples, under eyes, smile lines, marionette lines, and more. In addition, PRF BioFiller works as a Biostimulator, promoting the natural formation of new collagen and elastin for long-term rejuvenation. 

Hyperdilute Radiesse increases volume while stimulating collagen and elastin for long-term results.

PRF BioFiller combines many of the benefits of conventional dermal fillers with the benefits of biostimulators, but without any synthetic products or additives. PRF BioFiller is 100% natural, consisting only of parts of your blood that are prepared in a specific manner. PRF BioFiller is a great option for individuals looking to:

  • Improve volume loss without synthetic filler injections
  • Restore and refresh the under eye area 
  • Reduce hollowing of the temples
  • Minimize smile lines and marionette lines
  • Soften the appearance of lip lines/smoker’s lines
  • Stimulate natural collagen and elastin for improved skin quality

Quick Facts


Loss of Volume on the Face, Sagging Skin on the Face & Neck, Collagen & Elastin Loss, Crepey Skin, Fine Lines & Wrinkles, Skin Laxity

How It Works

Your blood is drawn and processed in a specific manner (without any additives) to create a growth factor-rich gel, which is then injected into the face and/or neck to restore volume and stimulate collagen production over time.


Minimal to None


Instant results with progressive rejuvenation over time. Annual maintenance treatments recommended.

Why PRF BioFiller?

PRF BioFiller is a 100% natural alternative to traditional filler that uses growth factors and proteins from your own blood to restore lost volume and stimulate collagen within the skin. It works much like fillers and biostimulators, and drastically outperforms PRP/PRF injections, but there are zero additives or synthetic ingredients.

What is PRF BioFiller?

PRF BioFiller combines the benefits of platelet-rich fibrin (PRF) — which is the next-generation alternative to platelet rich plasma (PRP) — with a protein matrix that is also derived from your own blood, allowing for volumization that lasts much longer than PRF/PRP injections alone. This allows PRF BioFiller to act much like a conventional dermal filler, but without any synthetic ingredients or additives. That means you can get many of the wonderful benefits of filler but with a 100% natural treatment!

How does PRF BioFiller work?

PRF BioFiller is created using proteins and compounds from your own blood. The process begins by drawing a small amount of your blood. We take half of the drawn blood and spin it in a specialized centrifuge to separate the PRF (platelet-rich fibrin) from the rest of the blood, and then centrifuge the other half to separate out the Albumin, which is a protein contained in your blood serum. The Albumin is then heated to a precise temperature to allow the proteins to unfold, then naturally refold into a different arrangement, which forms a gel-like substance. This Albumin gel is then mixed with your PRF at a specified ratio to form PRF BioFiller. Nothing is added to this solution — only the two parts of your blood. 

Once your PRF BioFiller is prepared, it can be injected just like a conventional filler or biostimulator would be. We recommend 2-3 treatments of PRF BioFiller, depending on your anatomy and your specific concerns and goals. Each treatment is typically spaced about 6 weeks apart for optimal results, with annual maintenance recommended. 

After injection, you will notice an immediate improvement in volume in the areas treated. Over the next several weeks, the PRF BioFiller will slowly integrate into your tissue, providing a slow release of growth factors for a naturally rejuvenated appearance. 

What is the process for PRF BioFiller treatments?

First, you will come in for a consultation with one of our experienced injectors to discuss your goals and the details of the treatment. The injector will assess your condition and create a treatment plan accordingly.

Before the the treatment, the area is numbed with a topical numbing cream and your blood is drawn. While you are numbing, your blood will be processed into PRF BioFiller, which is then strategically injected into your areas of concern. The procedure typically takes around 30-45 minutes, depending on your unique anatomy and the area being treated.

After the injections, the area may be massaged as needed to ensure even distribution. You can go back to your regular activities right away, although you may experience some swelling or bruising for a few days.

Typically, the treatment will be repeated about 6-8 weeks later for best results. While 2-3 treatments is common, the number of treatments will vary based on your individual case and goals. Volumization can be seen immediately. The PRF BioFiller will begin to integrate into your tissue over the following several weeks, and after this time, the extended-release growth factors will begin to release, stimulating.  

How much does PRF BioFiller cost in New Jersey?

The cost of PRF BioFiller varies based on your areas of concern, your anatomy, your skin condition, the number of treatments needed, the amount of product needed, and the experience of the injector. Call us at 877-750-0020 or text us at 201-425-0825 for a complimentary consultation, so we can determine the best treatment plan and quote accordingly.

PRF BioFiller FAQs

Who is PRF BioFiller for?

PRF BioFiller is a great option for those looking for a 100% natural alternative to fillers and biostimulators, as well as those looking to restore lost volume and stimulate collagen and elastin while maintaining a natural appearance.

How quickly can I expect results?

Improvement in volume can be seen immediately, while the final result continues to develop over the course of months after the treatment, as additional collagen and elastin are stimulated. 

How long do the results last?

Each individual is different, but the results are long-lasting. PRF BioFiller works a bit differently than filler, since it creates volume and also stimulates collagen and elastin, so your injector will explain the differences and set your expectations according to your case. We typically recommend annual maintenance treatments after your initial series.

How much downtime is there after each treatment?

There is no downtime after treatment. It is advised that you refrain from exercise, sweat, saunas, swimming, and sun exposure for 24 hours after treatment. You may experience some bruising and swelling which gradually subside.

Is the treatment painful, and are there side effects?

We use numbing agents and advanced injection techniques to minimize discomfort. Most individuals find the treatment to be comfortable. Common side effects include swelling, bruising, redness, and tenderness at the injection site, which typically resolve on their own within a few days, but since PRF BioFiller is 100% natural, additional side effects are extremely rare.

How many treatments do I need?

The number of treatments varies depending on your goals and current condition. In general, 2-3 treatments spaced by about 6-8 weeks each are recommended for best results. If more volume is desired, additional treatments can be performed.